Tuesday, December 23, 2008

A Seven-In-Absentia Approach to Pancreatic Cancer

Blocking Molecular Pathway With Whimsical Name Possible Therapeutic Target For Pancreatic Cancer is a Science Daily article about a potentially productive therapeutic approach to pancreatic cancer. The article points out that cancer of the pancreas is the most lethal of human cancers. A gene known as Seven-In-Absentia (SINA) is the focus of attention for its coded protein appears to perform a check and balance function within a pathway identified as K-RAS. The specifics entail neutralizing growth-promoting proteins through their degradation. Mutated K-RAS genes have been linked to excessive growth of cancerous pancreas cells.

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