Saturday, November 15, 2008

Alternative Splicing

Widespread Alternative Splicing is the title of this HUM-MOLGEN article. The article references a paper published in Nature. It begins by noting the remarkable fact that alternative splicing occurs with over 90% of human genes. Alternative splicing enables a single gene to yield a multiple variety of proteins.

The article also discloses that a common mechanism regulates both alternative splicing and polyadenylation. Polyadenylation involves adding adenine to ends of messenger RNA. This has the effect of providing it with stability.

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