A Gene Called p18 and Breast Cancer
Genetic Cause Of Most Common Form Of Breast Cancer Identified is a Science Daily article whose first paragraph is:
Researchers at the University of North Carolina at Chapel Hill School of Medicine and UNC Lineberger Comprehensive Cancer Center located a gene known as p18 whose malfunction may lead to cancer. A related paper appears in the May 2009 issue of Cancer Cell.
The gene p18 codes for a braking mechanism and when it is deleted or not expressed cellular replication may proceed unabated. The role of p18 in luminal breast cancers was a specific focus of researchers. Mice are used to test for effective tumor treatments.
The discovery of tumor-suppressor genes has been key to unlocking the molecular and cellular mechanisms leading to uncontrolled cell proliferation – the hallmark of cancer. Often, these genes will work in concert with others in a complex biochemical system that keeps our cells growing and dividing, disease free.
Researchers at the University of North Carolina at Chapel Hill School of Medicine and UNC Lineberger Comprehensive Cancer Center located a gene known as p18 whose malfunction may lead to cancer. A related paper appears in the May 2009 issue of Cancer Cell.
The gene p18 codes for a braking mechanism and when it is deleted or not expressed cellular replication may proceed unabated. The role of p18 in luminal breast cancers was a specific focus of researchers. Mice are used to test for effective tumor treatments.
Labels: Breast Cancer
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